[轉自： http://www.cnblogs.com/cenalulu/archive/2013/01/08/2850820.html]

原因1. MySQL 服務宕了

判斷是否屬於這個原因的方法很簡單，執行以下命令，檢視mysql的執行時長

$ mysql -uroot -p -e "show global status like 'uptime';"
+---------------+-------+
| Variable_name | Value |
+---------------+-------+
| Uptime        | 68928 |
+---------------+-------+
1 row in set (0.04 sec)

或者檢視MySQL的報錯日誌，看看有沒有重啟的資訊

$ tail /var/log/mysql/error.log
130101 22:22:30 InnoDB: Initializing buffer pool, size = 256.0M
130101 22:22:30 InnoDB: Completed initialization of buffer pool
130101 22:22:30 InnoDB: highest supported file format is Barracuda.
130101 22:22:30 InnoDB: 1.1.8 started; log sequence number 63444325509
130101 22:22:30 [Note] Server hostname (bind-address): '127.0.0.1'; port: 3306
130101 22:22:30 [Note]   - '127.0.0.1' resolves to '127.0.0.1';
130101 22:22:30 [Note] Server socket created on IP: '127.0.0.1'.
130101 22:22:30 [Note] Event Scheduler: Loaded 0 events
130101 22:22:30 [Note] /usr/sbin/mysqld: ready for connections.
Version: '5.5.28-cll'  socket: '/var/lib/mysql/mysql.sock'  port: 3306  MySQL Community Server (GPL)

如果uptime數值很大，表明mysql服務運行了很久了。說明最近服務沒有重啟過。

如果日誌沒有相關資訊，也表名mysql服務最近沒有重啟過，可以繼續檢查下面幾項內容。

2. 連線超時

如果程式使用的是長連線，則這種情況的可能性會比較大。

即，某個長連線很久沒有新的請求發起，達到了server端的timeout，被server強行關閉。

此後再通過這個connection發起查詢的時候，就會報錯server has gone away

$ mysql -uroot -p -e "show global variables like '%timeout';"
+----------------------------+----------+
| Variable_name              | Value    |
+----------------------------+----------+
| connect_timeout            | 30       |
| delayed_insert_timeout     | 300      |
| innodb_lock_wait_timeout   | 50       |
| innodb_rollback_on_timeout | OFF      |
| interactive_timeout        | 28800    |
| lock_wait_timeout          | 31536000 |
| net_read_timeout           | 30       |
| net_write_timeout          | 60       |
| slave_net_timeout          | 3600     |
| wait_timeout               | 28800    |
+----------------------------+----------+

mysql> SET SESSION wait_timeout=5;

## Wait 10 seconds

mysql> SELECT NOW();
ERROR 2006 (HY000): MySQL server has gone away
No connection. Trying to reconnect...
Connection id:    132361
Current database: *** NONE ***

+---------------------+
| NOW()               |
+---------------------+
| 2013-01-02 11:31:15 |
+---------------------+
1 row in set (0.00 sec)

3. 程序在server端被主動kill

這種情況和情況2相似，只是發起者是DBA或者其他job。發現有長時間的慢查詢執行kill xxx導致。

$ mysql -uroot -p -e "show global status like 'com_kill'"
+---------------+-------+
| Variable_name | Value |
+---------------+-------+
| Com_kill      | 0     |
+---------------+-------+

4. Your SQL statement was too large.

當查詢的結果集超過 max_allowed_packet 也會出現這樣的報錯。定位方法是打出相關報錯的語句。

用select * into outfile 的方式匯出到檔案，檢視檔案大小是否超過 max_allowed_packet ，如果超過則需要調整引數，或者優化語句。

mysql> show global variables like 'max_allowed_packet';
+--------------------+---------+
| Variable_name      | Value   |
+--------------------+---------+
| max_allowed_packet | 1048576 |
+--------------------+---------+
1 row in set (0.00 sec)

修改引數：

mysql> set global max_allowed_packet=1024*1024*16;
mysql> show global variables like 'max_allowed_packet';
+--------------------+----------+
| Variable_name      | Value    |
+--------------------+----------+
| max_allowed_packet | 16777216 |
+--------------------+----------+
1 row in set (0.00 sec)