Python sqlite3 模組它提供了一個SQL介面相容。不需要單獨安裝這個模組，因為它預設情況下隨著Python版本在2.5.x 一起安裝。

要使用sqlite3模組，必須首先建立一個連線物件，表示資料庫中，然後可以選擇建立遊標物件，這將幫助在執行的所有SQL語句。

（以下程式碼均在python 2.7.10下測試可行）

1、連線到資料庫
Python程式碼顯示瞭如何連線到一個現有的資料庫。如果資料庫不存在，那麼它就會被建立，終於將返回一個數據庫物件

#coding=utf-8
import sqlite3

#開啟一個數據庫，如果沒有則會自動建立一個，
conn = sqlite3.connect('test.db'
 
)#在當前位置，建立（硬碟上）
#conn = sqlite3.connect('memory')#在記憶體中建立（RAM）

print "Opened database successfully"

2、建立表
以下Python程式將使用以前建立的資料庫中建立一個表：

import sqlite3

conn = sqlite3.connect('test.db')
print "Opened database successfully";

conn.execute('''CREATE TABLE COMPANY
       (ID INT PRIMARY KEY     NOT NULL,
       NAME           TEXT    NOT NULL,
       AGE            INT     NOT NULL,
       ADDRESS        CHAR(50),
       SALARY         REAL);'''
 
)
print "Table created successfully";

conn.close()

3、INSERT 操作
Python程式顯示了我們如何能夠建立表COMPANY 在上面的例子中建立表中的記錄：

import sqlite3

conn = sqlite3.connect('test.db')
print "Opened database successfully";

conn.execute("INSERT INTO COMPANY (ID,NAME,AGE,ADDRESS,SALARY) \
      VALUES (1, 'Paul', 32, 'California'
 
, 20000.00 )");

conn.execute("INSERT INTO COMPANY (ID,NAME,AGE,ADDRESS,SALARY) \
      VALUES (2, 'Allen', 25, 'Texas', 15000.00 )");

conn.execute("INSERT INTO COMPANY (ID,NAME,AGE,ADDRESS,SALARY) \
      VALUES (3, 'Teddy', 23, 'Norway', 20000.00 )");

conn.execute("INSERT INTO COMPANY (ID,NAME,AGE,ADDRESS,SALARY) \
      VALUES (4, 'Mark', 25, 'Rich-Mond ', 65000.00 )");

conn.commit()
print "Records created successfully";
conn.close()

4、SELECT 操作
Python程式，表明我們如何能夠獲取並顯示COMPANY 在上面的例子中建立表的記錄：

import sqlite3

conn = sqlite3.connect('test.db')
print "Opened database successfully";

cursor = conn.execute("SELECT id, name, address, salary  from COMPANY")
for row in cursor:
   print "ID = ", row[0]
   print "NAME = ", row[1]
   print "ADDRESS = ", row[2]
   print "SALARY = ", row[3], "\n"

print "Operation done successfully";
conn.close()

5、UPDATE 操作
Python程式碼顯示如何，我們可以使用UPDATE語句來更新任何記錄，然後獲取並顯示更新的記錄，從COMPANY 表：

import sqlite3

conn = sqlite3.connect('test.db')
print "Opened database successfully";

conn.execute("UPDATE COMPANY set SALARY = 25000.00 where ID=1")
conn.commit
print "Total number of rows updated :", conn.total_changes

cursor = conn.execute("SELECT id, name, address, salary  from COMPANY")
for row in cursor:
   print "ID = ", row[0]
   print "NAME = ", row[1]
   print "ADDRESS = ", row[2]
   print "SALARY = ", row[3], "\n"

print "Operation done successfully";
conn.close()

6、DELETE 操作
Python程式碼顯示瞭如何我們可以使用DELETE語句刪除任何記錄，然後獲取並顯示剩餘的記錄COMPANY 表：

import sqlite3

conn = sqlite3.connect('test.db')
print "Opened database successfully";

conn.execute("DELETE from COMPANY where ID=2;")
conn.commit
print "Total number of rows deleted :", conn.total_changes

cursor = conn.execute("SELECT id, name, address, salary  from COMPANY")
for row in cursor:
   print "ID = ", row[0]
   print "NAME = ", row[1]
   print "ADDRESS = ", row[2]
   print "SALARY = ", row[3], "\n"

print "Operation done successfully";
conn.close()